Abstract
Objectives: To assess the effectiveness, side effects of two regimens using Nifedipine or Magnesium sulfate in the treatment of preterm labor.
Materials and methods: Prospective study included 114 patients diagnosed and treated for preterm labor in Department of Obstetrics and Gynecology, Hue Central Hospital and University Hospital of Medicine and Pharmacy Hue from May 2010 to June 2011. After diagnosis, patients have been randomly assigned into 2 groups receiving magnesium sulfate or nifedipine; assessment of efficacy and safety of each treatment regimen.
Results: The rate of tocolysis in the Magnesium sulfate group was 91.2% and Nifedipine group was 89.5%. Tocolysis time in the Magnesium sulfate group was 12.4 ± 35.8 minutes, in group Nifedipine was 90.58 ± 19.5 minutes. When cervical dilatation < 2 cm, the success rate of Magnesium sulfate was 94.2%, those of Nifedipine was 90.1%. When cervical dilatation ≥ 2cm, the success rate of Magnesium sulfate was 60% and those of Nifedipine was 33.3%. The success rate of prolonged gestation ≥ 48 hours seen mainly in preterm labor with tocolysis index of 2 or 3 points, 97.7% and 94.2%, respectively. In the Magnesium sulfate group, prolonged gestation ≥ 48 hours obtained in 91.2% of cases, mean prolongation of gestation 26.3 ± 19.5 day; in the Nifedipine group: prolonged gestation ≥ 48 hours obtained in 93% of cases, mean prolongation of gestation 21.5 ± 14.4 day.
Conclusion: Magnesium sulfate and Nifedipine regimen yielded high efficiency and safety for pregnant women and fetuses in the treatment of preterm labor.
Tạp chí sẽ lưu giữ bản quyền phân phối, giao dịch đối với tất cả các bản thảo, bản toàn văn của bài báo đăng trên hệ thống. Mọi hình thức chia sẽ, trao đổi, giao dịch các sản phẩm thuộc hệ thống xuất bản vjog.vn mà không được sự đồng ý của chúng tôi sẽ là vi phạm bản quyền
Downloads
Most read articles by the same author(s)
- Bao Nhan Hoang, Vu Quoc Huy Nguyen, Meconium stained amniotic fluid in term pregnancies: Some risk factors and outcomes , Vietnam Journal of Obstetrics & Gynecology: Vol. 11 No. 1 (2013)
- Vu Quoc Huy Nguyen, Minh Tam Le, Quang Vinh Dang Cong Thuan Truong, Ngoc Thanh Cao, Screening of cervical pre-invasive lesions and invasive cancer by Pap-smear , Vietnam Journal of Obstetrics & Gynecology: Vol. 11 No. 1 (2013)
- Viet Nhan Nguyen, Ngoc Thanh Cao, Thi Minh Thi Ha, Vu Quoc Huy Nguyen, Van Duc Vo, Quang Vinh Truong, Manh Linh Tran, Role of sFLT-1/PLGF ratio for prediction and diagnosis of pre- eclampsia , Vietnam Journal of Obstetrics & Gynecology: Vol. 13 No. 4 (2016)
- Duc Tam Lam, Vu Quoc Huy Nguyen, Treatment result of cervical lesions by cryotherapy in Can Tho , Vietnam Journal of Obstetrics & Gynecology: Vol. 13 No. 4 (2016)
- Dang Hieu Mai, Vu Quoc Huy Nguyen, Đặc điểm của siêu âm, nhũ ảnh và chọc hút tế bào kim nhỏ trong chẩn đoán u vú , Vietnam Journal of Obstetrics & Gynecology: Vol. 13 No. 4 (2016)
- Quang Vinh Truong, Ngoc Thanh Cao, Vu Quoc Huy Nguyen, Van Duc Vo, Viet Nhan Nguyen, Manh Linh Tran, Prediction of preeclampsia by arterial pressure at 11+0 to 13+6 weeks’ gestation , Vietnam Journal of Obstetrics & Gynecology: Vol. 14 No. 2 (2016)
- Thi Linh Giang Truong, Vu Quoc Huy Nguyen, The value of the middle cerebral to umbilical artery doppler ratio in prediction of neonatal outcome in patient with preeclampsia , Vietnam Journal of Obstetrics & Gynecology: Vol. 14 No. 3 (2016)
- Duc Tam Lam, Thi Tram Anh Luu, Vu Quoc Huy Nguyen, Rate of fetal macrosomia and factors related to fetal macrosomia at Cantho Hospital of Obstetrics and Gynecology in 2015 , Vietnam Journal of Obstetrics & Gynecology: Vol. 14 No. 3 (2016)
- Dinh Phuong Thao Nguyen, Ngoc Thanh Cao, Vu Quoc Huy Nguyen, Effects of estradiol therapy in vascular disorders and psychological disorders in post-menopausal women , Vietnam Journal of Obstetrics & Gynecology: Vol. 14 No. 3 (2016)
- Ngoc Thanh Cao, Van Duc Vo, Vu Quoc Huy Nguyen, Quang Vinh Truong, Viet Nhan Nguyen, Thi Minh Thi Ha, Tran Thao Nguyen Nguyen, Manh Linh Tran, Maternal serum PAPP-A levels at 11+0–13+6 weeks of gestation in the prediction of hypertension disorder , Vietnam Journal of Obstetrics & Gynecology: Vol. 13 No. 1 (2015)