Research of progesteron value in early diagnosis and response to medical therapy ectopic pregnancy

Abstract

Objectives: 1. To investigate the value of progesteron and β-hCG in the early diagnosis of ectopic pregnancy. To evaluate the relationship between progesteron, β-hCG level and medical treatment outcomes. Materials & Methods: From 5/2012 to 7/2012, at the Department of Obstetric and Gynecology, descriptive study on 161 patients to study the value of progesteron and β-hCG in the early diagnosis of ectopic pregnancy. Prospectively cohort study on 33 patients to assess the relationship between progesteron, β-hCG for medical treatment results. Results: The average level of β-hCG in ectopic pregnancy group was 1530 (403.9, 5371) mIU/ml. Average progesteron levels in ectopic pregnancy group was 5.18 (2.07, 11.7) ng/ml. In cases having progesteron levelsless than 5 ng/ml, treatment success rate is 100%; while progesteron greater than 15 ng/ml did not have any cases of successful treatment (p = 0.008). In cases having of β-hCG level less than 2000 mIU/ml, the treatment success rate is 100%, β-hCG > 5000 mIU/ml did not have any cases successfully treated (p = 0.002). Conclusion: Progesteron and β-hCG level could be used in the prognosis and monitoring treatment outcomes of ectopic pregnancy.