Abstract
Objective: Describe the chromosomal characteristics fetuses with tetralogy of fallot (TOF).
Material and Methods: Cross – section study 51 fetuses diagnosed TOF, all cases were taken amniotic and used the BoBs technique and karyotyping to analyze fetal chromosomes
Results: Among the 51 fetuses with TOF: the average gestational age at ultrasound was 22.2 weeks, the age of amniocentesis was 23.1 weeks. The rate of fetuses with only TOF was 86.3%, and TOF with extracardiac anomalies was 11.7%. The rate of chromosomal abnormalities was 29.4% (15/51). In which the abnormal number of chromosomes was 6/15 and abnormal structure was 9/15. In abnormal group of chromosome structure, Digeorge syndrome was recorded for a large number of 8/9 cases.
Conclusion: Detection of fetal chromosomal abnormalities with TOF is the basis for obstetricians to perform genetic counseling and prenatal diagnosis.
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