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Abstract
Objective: To describe the relationship between HPV high-risk infection and cervical cancer in Vietnam 2003.
Methodology: Case-control study design was applied. The number of cervical cancer patients was 100 and the same number among the control group.
Results: There was a close relationship between HPV infection and cervical cancer. Those who infected by HPV were more frequently having cervical cancer than the others (OR=495,4 and 95%CI: 104,26-2354,30; pYates< p<0,0001). There was a close relationship between HPV type 16, 18 and cervical cancer. Among 100 cervical cancer, there were 91 patients with HPV infected (91%). 46% of cervical cancer patients infected by HPV type 16 and 19% of them with HPV type 18. The number of cervical cancer patients infected by HPV type 11 was 12%. Other types 6, 33, 58 of HPV were met among cervical cancer patients (2-3%). Percentage of patients with two types of HPV at the same time was 5%.
Discussion: In many studies, the high-risk types of HPVwere causes of cervical cancer. 12 high-risk types of HPV were confirmed as causes of cervical cancer (HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58). In Vietnam, HPV type16 and 18 were considered as twohigh-risk typesof cervical cancer. In addition, HPV types 6 and 11 were also caused cervical cancer. Conclusion: There was a close relationshipbetween HPV infected and cervical cancer, especially HPV types 16, 18. Other types of HPV as 6, 11, 16, 18, 33, 35, 51, 52, 58, 68 were found in the cervical cancer patients.
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