Value of nuchal translucency to diagnosis abnomalities in fetus with normal karyotype

Abstract

Objective: To estimate the rate of malformations and adverse outcome of chromosomally normal pregnancies with increased nuchal translucency at the 12-14 weeks scan. Materials and methods: Retrospective study of 380 chromosomally normal singleton pregnancies with nuchal translucency of ≥ 3,0mm. These patients were managed with follow-up scans at 22, 28, 32 weeks in the center of prenatal diagnosis of NHOG from 01/2011 to 04/2013. Results: for all cases increased NT, 85,8% has normal karyotype. Among those 380 pregnancies, 10,2% has malformations such as: heart defects, diagphragmatic hernia, neural tube, chest, and abdominal abnomalies. The rate of adverse outcome pregnancy is 5,8%. Conclusions: pregnancy women who have fetus increased NT need to have ultrasonography check up regulary in order to control others abnomalities.