Congenital Rubella Syndrome at Newborn Center, National hospital of Obstetrics and Gynecology

Abstract

This study described the characteristics of Congenital Rubella Syndrome (CRS) in Rubella treatment service in Newborn Treatment Center, National hospital of Obstetrics and Gynecology (NHOG), in the North of Vietnam 2011.

Objectives: to evaluate the prevalence of CRS post-partum and describe clinical abnormalities and bio-chemical test among those.

Materials and methods: This is a cross-sectional study with newborns, who were delivered at NHOG from 1/8 to 31/10/2011, were diagnosed with CRS and their mothers also had Rubella or suspected with.

Results: the prevalence of newborns with CRS is 42.9%, 57.1% with Congenital Rubella Infection (CRI) and 14.3% mothers had no symptoms. Newborn with CRS had the common symptoms such as 60% Thrombocytopenia,55,7% increase SGOT, 44,3% glycemia, neonatal infection 22,9%, post-delivery mortality 5,7%, congenital heart disease 38,6%, problems with eyes 12,9%, screening for inborn deaf is not applied yet.

Conclusion: Newborns with CRS took 40% as a whole, and newborns have Rubella symptom is 60% and 14% mother delivered babies with CRS without symptoms. Common characteristics of CRS is malnutrition, microcephaly, intraventricular hemorrhage, positive IgG and IgM test, thrombocytopenia, increase SGOT, hypoglycemia, congenital heart defects, newborn infection and possibility of post-delivery mortality.