Ngôn ngữ sử dụng
Cách trích dẫn
Tóm tắt
Objectives: To evaluate treatment results of stillbirth in the first trimester of pregnancy and related factors. Methods: A cross-sectional study with all cases of cessation of fetal progression in the first trimester of pregnancy diagnosed and treated at the Department of Obstetrics and Gynecology - Hue University of Medicine and Pharmacy Hospital from May 2023 to November 2023.
Results: Through a study of 121 cases of stillbirth in the first trimester of pregnancy, 10 cases of spontaneous abortion were recorded after admission to the hospital (8.3%). The success rate with medical abortion is 97.3%, of which the complete miscarriage rate is 92.8%. There were 8 cases of intervention treatment (suction curettage or vacuum aspiration) (6.6%), the success rate was 100%. Most medical treatments are successful after 1 course, the average number of doses of misoprostol for abortion is 2.1 ± 1.1 doses with an average total dose of 1250.0 ± 667.0 µg. The average time to expulsion is 16.5 ± 14.1 hours. A history of preterm birth increased the rate of incomplete miscarriage by 16.5 times (16.5; 95%CI: 2.1 - 128.1).
Conclusion: Medical treatment of stillbir th in the first trimester of pregnancy has high success rate with a short treatment course and duration.
Tài liệu tham khảo
2. American College of Obstetricians and Gynecologists (2018), "Early pregnancy loss ", Practice Bulletin - Gynecology 200, pp.1258-1267.
3. Le Van Thuong, Le Van An, Nguyen Vu Quoc Huy (1994), "Preliminary assessment of the epidemiology, pathology and treatment of stillbirth at the obstetrics department of Hue Central Hospital in 3 years 1991-1994", Scientific Research Information Journal, 4, p.149-154.
4. Department of Obstetrics and Gynecology - Hue University of Medicine and Pharmacy (2021), "Fetal death in utero ", Textbook Module 19 - Obstetrics 1 , p.222-229.
5. Vo Dang Que (2022), Research on clinical and paraclinical characteristics and results treatment of intrauterine fetal death with Misoprostol in the first trimester of pregnancy at Quang Ngai Obstetrics and Pediatrics Hospital , Specialist thesis Level II, Hue University of Medicine and Pharmacy .
6. Nguyen Thi Thanh Hang (2022), Research on clinical and paraclinical characteristics and results treatment of intrauterine fetal death ≤ 12 weeks of gestation with old cesarean section incision , Master's thesis in Medicine, Hue University of Medicine and Pharmacy.
7. Bui Thi Nhu Quynh, Vo Van Duc, Le Minh Tam (2017), "Research on the results of treating cessation of fetal progression in the first trimester with Misoprostol” , Journal of Obstetrics and Gynecology, 15(1), p.51-56.
8. Truong Minh Kien (2010), "Research on application of Misoprostol to terminate pregnancy on intrauterine death in the first trimester of pregnancy at Can Tho Central General Hospital", Ho Chi Minh City Association of Reproductive Endocrinology and Infertility .
9. Elizabeth GR Margo SH Mark A. W (2018), "Efficacy of Misoprostol Alone for First-Trimester medical Abortion " , A Systematic Review , pp.137-147.
10. Nguyen Thi Huyen Trang, et al (2017), "Evaluating the effectiveness of Misoprostol in the treatment of intrauterine arrest of pregnancy less than or equal to 12 weeks at the obstetrics department of Military Hospital 175" , Medical Journal Practical Pharmacy 175 , 12, p.55-64.
11. Le Diem, Le Hoang (2000), "High-risk pregnancy ", Pathology Encyclopedia , Hanoi Medical Publishing House, p.405-407.
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