Tóm tắt
Objectives: To determine the prevalence of low genital tract colonization by Mycoplasma, Ureaplasma and its association with bacterial vaginosis
Materials and Methods: A cross-sectional study carry on 802 women who were visited at Vinmec International Hospital from January 2021 to January 2022. M. genitalium, M. hominis, U. urealyticum, U. parvum in low genital tract sample were detected by Realtime - PCR method. Diagnosis of bacterial vaginosis based on microbiological morphology according to Nugent score. Abnormal cases are treated and followed.
Results: The prevalence of M. genitalium was 1.6% (95%CI: 0.9 - 2.8), M. hominis was 5.0% (95%CI: 3.6 – 6.8), U. urealyticum was 13.1% (95%CI: 10.7 - 15.9) and U. parvum was 36.0% (95%CI: 32.0 - 40.4). Mycoplasma and Ureaplasma present in lower genital tract samples were not associated with clinical symptoms. The rate of bacterial vaginosis was 4.7% and it was not associated with the presence of M. genitalium, M. hominis, U. urealyticum, U. parvum in low genital tract.
Conclusion: The prevalence of Mycoplasma and Ureaplasma in the genital tract is relatively low and it was not associated with bacterial vaginosis.
Tài liệu tham khảo
2. Jensen JS, Cusini M, Gomberg M, Moi H, Wilson J, Unemo M. 2021 European guideline on the management of Mycoplasma genitalium infections. Acad Dermatol Venereol [Internet]. 2022 May [cited 2022 Nov 29];36(5):641–50. Available from: https://onlinelibrary.wiley.com/doi/10.1111/jdv.17972
3. Taylor-Robinson D. Mollicutes in vaginal microbiology: Mycoplasma hominis, Ureaplasma urealyticum, Ureaplasma parvum and Mycoplasma genitalium. Research in Microbiology [Internet]. 2017 Nov [cited 2022 Nov 29];168(9–10):875–81. Available from: https://linkinghub.elsevier.com/retrieve/pii/S092325081730044X
4. Romero R, Hassan SS, Gajer P, Tarca AL, Fadrosh DW, Nikita L, et al. The composition and stability of the vaginal microbiota of normal pregnant women is different from that of non-pregnant women. Microbiome [Internet]. 2014 Dec [cited 2022 Dec 11];2(1):4. Available from: https://microbiomejournal.biomedcentral.com/articles/10.1186/2049-2618-2-4
5. Waites KB, Schelonka RL, Xiao L, Grigsby PL, Novy MJ. Congenital and opportunistic infections: Ureaplasma species and Mycoplasma hominis. Seminars in Fetal and Neonatal Medicine [Internet]. 2009 Aug [cited 2022 Nov 29];14(4):190–9. Available from: https://linkinghub.elsevier.com/retrieve/pii/S1744165X08001467
6. Workowski KA, Bachmann LH, Chan PA, Johnston CM, Muzny CA, Park I, et al. Sexually Transmitted Infections Treatment Guidelines, 2021. 2021;70(4):192.
7. Le MT, Le QD, Nguyen VQH, Ngo VQT, Nguyen HB. Prevalence and risk factors of Ureplasma urealyticum and Mycoplasma genitalium among women with secondary infertility in Vietnam – A cross-sectional study. MedPharmRes [Internet]. 2020 Jun 16 [cited 2022 Nov 30];4(2):16–22. Available from: http://medpharmres.com/article-volume-2020-issue-2-4-2-16
8. Olsen B, Lan P, Stålsby Lundborg C, Khang T, Unemo M. Population-based assessment of Mycoplasma genitalium in Vietnam - low prevalence among married women of reproductive age in a rural area. Journal of the European Academy of Dermatology and Venereology [Internet]. 2009 May [cited 2022 Nov 30];23(5):533–7. Available from: https://onlinelibrary.wiley.com/doi/10.1111/j.1468-3083.2009.03117.x
9. Donders GGG, Ruban K, Bellen G, Petricevic L. Mycoplasma/Ureaplasma infection in pregnancy: to screen or not to screen. Journal of Perinatal Medicine [Internet]. 2017 Jan 26 [cited 2022 Nov 30];45(5). Available from: https://www.degruyter.com/document/doi/10.1515/jpm-2016-0111/html
10. Max Chernesky, David Patrick, Rosanna Peeling. Canadian laboratory standards for sexually transmitted infections: Best practice guidelines. The Canadian Journal of Infectious Diseases & Medical Microbiology. 2005 Feb;16(1).
11. Lee S, Romero R, Kim E, Yoon G. A high Nugent score but not a positive culture for genital mycoplasmas is a risk factor for spontaneous preterm birth. 2013;
Công trình này được cấp phép theo Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. . p>